Graham Potter makes his return to Stamford Bridge as he leads West Ham United across the capital for a showdown against his former club, Chelsea.
Newcastle United remain on course for European qualification as they welcome a Fulham side coming off a recent home defeat to Manchester United.
Kieran McKenna and Ivan Juric will be eager to secure three points, with both of their teams battling near the lower end of the Premier League standings.
David Moyes aims to secure his second victory at Goodison Park since returning as Everton’s manager, as his team prepares to face Leicester City.
Third-positioned Nottingham Forest will aim to recover from their recent loss as they face a Brighton & Hove Albion team that has shown strength on the road.
On Monday night, a significant showdown unfolds in the Championship's battle for automatic promotion, featuring Leeds United against Burnley.
Fulham welcome Manchester United to Craven Cottage in the Premier League, aiming to secure back-to-back victories and narrow the gap to the European qualification spots.
Aston Villa and West Ham face off at Villa Park this weekend in what some humorously dub the "David Cameron Derby," with both teams eager to secure a much-needed victory.
Tottenham Hotspur welcome Leicester City to their home ground in the Premier League, as both sides aim to secure three crucial points and put an end to their recent struggles.
Crystal Palace will encounter their second London Derby within a week, with Brentford journeying across the city to Selhurst Park.